ACADEMIC AND HOSPITAL APPOINTMENTS

9/14 – present:  Assistant Professor of Psychiatry, Columbia University Medical Center, New York, NY

9/13 – present:  Emergency Room Psychiatrist Per Diem, Veteran’s Agency New York Harbor Healthcare, New York, NY

7/12 – 9/14:  Postdoctoral Research Fellow in Affective Disorders, Columbia University Medical Center, New York, NY

7/12 – 7/13:  Clinical Instructor, State University of New York, Stony Brook, NY

9/98 – 3/01: Research Assistant, Rockefeller University, New York, NY

6/97 – 5/98 Research Assistant, Wesleyan University, Middletown, CT

EDUCATION

5/11/08 8/01 – 5/08: Duke University School of Medicine, Durham, NC MD, 10/25/08

7/03 – 10/08: Cambridge University, Cambridge, UK; PhD Thesis: “Molecular Studies to Further Understand the Pathophysiology and Treatment of Bipolar Affective Disorder” Thesis Advisors: Dr. Sabine Bahn and Dr. Husseini Manji PhD

9/94 – 5/98: Wesleyan University, Middletown, CT Senior Honors Thesis: “The Synthesis of Three Novel b-lactamase Inhibitors and Initial Kinetic Studies of their Inhibitory Effects” Thesis Advisor: Dr. Rex Pratt BA, 5/98

TRAINING

6/09 – 6/12:  Psychiatry Residency, New York Presbyterian Hospital/Weill Cornell, New York, NY

6/08 – 6/09: Internship, New York Presbyterian Hospital/Weill Cornell, New York, NY

LICENSURE

2/10 – present:  New York State Medical License

BOARD CERTIFICATION

11/12 – present: Diplomat of the American Board of Psychiatry and Neurology

HONORS

2014: Invited guest speaker at the annual meeting of the New York State National Alliance on Mental Illness

2012: New York State Psychiatric Association Annual Scientific Paper Contest Second Place Winner

1998: Honors in Molecular Biology and Biochemistry, Wesleyan University

PROFESSIONAL ORGANIZATIONS

1/08 – present: Member, American Psychiatric Association

FELLOWSHIP AND GRANT SUPPORT

9/25/14 – present: Serotonin 1A Receptor PET Imaging and SSRI Outcome in Bipolar Depression NIMH, K23 MH105688-01 Role: Principal Investigator

9/14 – 5/16: Identification of Biosignatures for Lurasidone (Latuda) Response in Bipolar Depression Independent Medical Education Grant, Sunovian Pharmaceuticals Role: Co-Investigator (PI: McGrath)

8/03 – 5/08: National Institutes of Health Graduate Partnership Program Medical Scientist Training Program for PhD and Medical School

1997: Howard Hughes Grant for summer undergraduate research

EDUCATIONAL CONTRIBUTIONS

7/13 – 7/15: Clinical supervisor of third year psychiatry resident for psychopharmacology training New York Presbyterian Hospital/Columbia University

7/12 – 7/13: Clinical supervisor of second year psychiatry residents for mental health clinic evaluation service New York Presbyterian Hospital/Columbia University Educational Administration and Leadership

8/11: Led a second year medical student seminar to teach the fundamentals of the mental status exam, Cornell University Medical School

PUBLICATIONS

1. Lan MJ, Chhetry BT, Liston C, Mann JJ, Dubin M “Transcranial Magnetic Stimaulation of Left Dorsolateral Prefrontal Cortex Induces Brain Morphological Changes in Regions Associated with a Treatment Resistant Major Depressive Episode: An Exploratory Analysis” Brain Stimulation 2016 epub

2. Lan MJ, Ogden RT, Huang Y, Oquendo MA, Sullivan GM, Miller J, Milak M, Mann JJ, Parsey RV “Genetic Variation in Brain Derived Neurotrophic Factor val66met Allele is Associated with Altered Serotonin-1A Receptor Binding in Human Brain” Neuroimage 2014; 94: 33-39.

3. Lan MJ, Chhetry BT, Oquendo ME, Sullivan GM, Mann JJ, Parsey RV “Cortical Thickness Differences Between Bipolar Depression and Major Depressive Disorder”, Bipolar Disorders 2014; 16: 378-388.

4. Lan MJ, Hasselgrave N, Ciarleglio A, Ogden, RT, Mann JJ, Parsey RV “Higher 5HT-1A Receptor Binding Potential in Depressed Bipolar Disorder Patients Predicts Treatment Remission: Preliminary Data from a Naturalistic Study”, Synapse 2013; 67: 773-778.

5. Giger T, Khaitovich P, Somel M, Lorenc A, Lizano E, Harris L, Ryan M, Lan M, Wayland M, Bahn S, Paabo S.: Evolution of Neuronal and Endothelial Transcriptomes in Primates. Genome Biology and Evolution 2010; 12: 284-292

6. Harris L W, Wayland M, Lan M, Ryan M, Giger T, Lockstone H, Wuethrich I, Mimmack M, Wang L, Kotter M, Craddock R, Bahn S.: The Cerebral Microvasculature in Schizophrenia: A Laser Capture Microdissection Study. PLoS One 2008; 3: e3964

7. Lan MJ*, McGloughlin GA, Griffin JL, Tsang TM, Huang JT, Yuan P, Manji H, Holmes E, Bahn S: Metabolomic Analysis Identifies Molecular Changes Common to the Treatment and Pathophysiology of Bipolar Disorder. Molecular Psychiatry 2008; 14: 269-279. *Lan MJ is co-first author with McGloughlin GA.

8. Lan MJ, Yuan P, Chen G, Manji HK.: Neuronal Peroxisome Proliferator-activated Receptor Gamma Signaling: Regulation by Mood-stabilizer Valproate. Journal of Molecular Neuroscience 2008; 35: 225-234

9. Kaur K, Adediran SA, Lan MJ, Pratt RF: Inhibition of Beta-lactamases by Monocyclic Acyl Phosph(on)ates. Biochemistry 2003; 42: 1529-36

10. Bibb JA, Nishi A, O’Callaghan JP, Ule J, Lan M, Snyder GL, Horiuchi A, Saito T, Hisanaga, S, Czernik AJ, Nairn AC, Greengard P: Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5. The Journal of Biological Chemistry 2001; 278: 12290-12297

11. Kaur K., Lan MJ, Pratt RF: Mechanism of the Inhibition of the Class C -lactamase of Enterobacter cloacae P99 by cyclic Acyl Phos(phon)ates: Rescue by Return. J Am Chem Soc. 2001; 123: 10436

Reviews and Chapters

1. Lan MJ and Mann JJ (2016) “Serotonergic Dysfunction in Bipolar Disorder” in Bipolar Disorders: Basic Mechanisms and Therapeutic Implications, Third Edition, Soares JC and Young A, Cambridge Univerisity Press

2. Lan MJ and Parsey RV (2013) “Brain Imaging” in The Clinical Handbook for the Management of Mood Disorders, Mann JJ, McGrath PJ and Roose SP, New York: Cambridge University Press

3. Schlosser R, Lan M, Manji H (2009) “Neurodegeneration in Psychiatric Illness” in Encyclopedia of Neuroscience Squire L, New York: Elselvier

4. Yuan P, Gould T.D., Gray N.A., Bachmann R.F., Schloesser R.J., Lan M, Du J., Moore G.J, Manji H. K: Neurotrophic Signaling Cascades are Major Long-term Targets for Lithium: Clinical Implications. Clinical Neuroscience Research 2004; 4: 137-153

Other Non-Peer Reviewed Publications in Print or Other Media

1. International Conference on Bipolar Disorders, Miami Beach, Fla 2013; Poster presentation. Lan MJ, Ogden RT, Huang Y, Oquendo MA, Sullivan GM, Miller J, Milak M, Mann JJ, Parsey RV “Genetic Variation in Brain Derived Neurotrophic Factor val66met Allele is Associated with Altered Serotonin-1A Receptor Binding in Human Brain”

2. Society of Biological Psychiatry, Philadelphia, PA 2012; Poster presentation. Lan MJ, Hasselgrave N, Ciarleglio A, Ogden RT, Sullivan GM, Mann JJ, Parsey RV “Higher 5-HT1A Receptor Binding Potential in Bipolar Disorder Depression Predicts Treatment Remission: A Naturalistic Treatment Pilot PET Study”

3. American College of Neuropsychopharmacology, Boca Raton, FL 2007: Poster presentation. Lan M, McGlouchlin G, Griffin J, Yuan P, Manji H, Bahn S “Metabolic Changes Common the the Treatment and Pathophysiology of Bipolar Disorder”

4. Society for Neuroscience, Washington DC, 2005: Poster presentation. Lan M, Yuan P, Zhou R, Du J, Manji HK “Chronic Valproic Acid Treatment Downregulates the Peroxisomal Matrix Proteins, Acyl CoA Oxidase and Catalase”